Design and Evaluation of a Brinzolamide Drug–Resin <i>in Situ</i> Thermosensitive Gelling System for Sustained Ophthalmic Drug Delivery
نویسندگان
چکیده
منابع مشابه
In situ gelling polyvalerolactone-based thermosensitive hydrogel for sustained drug delivery.
Biodegradable poly(ethyleneglycol)-poly(valerolactone)-poly(ethyleneglycol) [PEG-PVL-PEG] copolymers were synthesized through ring opening polymerization of δ-valerolactone (VL) followed by the coupling of monomethoxy poly(ethyleneglycol-poly(valerolactone) (mPEG-PVL) with hexamethylene diisocyanate (HDI). The copolymers were characterized by (1)H NMR, FT-IR, and GPC. Block copolymers of PEG an...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2014
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c14-00451